Oral Desquamations of Clinical Interest: A Report of 2 Cases

In oral medicine, dermatologic diseases have special attention as oral mucosal lesions may be a clinical feature or the only sign of various mucocutaneous diseases. Dentists are often the first to be consulted by patients who develop acutely painful oral ulcerations associated with these mucocutaneous lesions, and this could be neglected by dentists due to a lack of information and/or an improper diagnosis, leading to a significant deterioration in the quality of life of patients. This present article describes two variants of vesiculobullous lesions with a brief review, as they are a distinct group of oral disorders characterised by formations of vesicles or bullae. The dental practitioner attempting to diagnose the oral ulcers and lesions is often confronted with several diseases having similar and identical clinical appearances. Also, the clinical identification of intact vesicles and bullae in the oral cavity is really a challenge due to regular irritation and the friable nature of the oral mucosa, which makes the diagnosis of vesiculobullous lesions even more difficult as the differential diagnosis of the disease also includes ulcerative, immunological, neoplastic, and systemic diseases. So, here we present two diagnosed cases of vesiculobullous lesions affecting middle aged women who presented with an overlapping clinical presentation and a varying etiological factor. They were discussed with the aim of making a closer attempt to understand their clinical presentation, pathogenesis, diagnostic criteria, and early, effective management protocols for a better prognosis.