Biochemical Study of Gender Effect on Thyroid Cancer in the Egyptian Population

Background and Objective: Thyroid is one of the largest glands; its hormones affect almost every cell in the body, the incidence of thyroid cancer has raised in recent years, About 52,070 new cases of thyroid cancer in the United States in 2018 only. This study was undertaken to determine if gender was associated with susceptibility of thyroid cancer.

Materials and Methods: This study was carried out on 174 cases divided into 108 thyroid patients and 66 healthy as controls. The mean age of cases was (40.58±1.46) they include 48 female and 18 males. All participants were subjected to an estimation of thyroid stimulating hormone (TSH), free thyroxine (FT4), total antioxidant capacity (TAC), in addition to malondialdehyde (MDA).

Results: For TSH results that was an obvious effect of gender on TC, while for FT4 there was an effect of gender on thyroiditis and TC, for TAC there was a biting effect on thyroiditis and TC, for MDA there was an effect also on thyroiditis and TC, for tissue TAC (TTAC) that was a clear effect of gender on both thyroiditis and TC, and for TMDA there was a little effect.

Conclusion: Gender of TC patients effects on biochemical investigations of the thyroid.