Protective Effect of Raphanus sativus Using by Phytochemical and Antiulcer Activity by Aspirin Induced Gastric Ulcer

Raphanus sativus, a widely growing, has been used in traditional medicine for treating many ailments. The objective of the present study was to evaluate the effects of Aspirinic extract of R. Sativus leaves on gastric ulcer. The antiulcer effects of MERS at 100 and 200 mg/kg doses were evaluated on Aspirin gastric ulcer models. The histological changes in gastric tissue of ulcer mice were also determined in aspirin induced models. R. sativus treatment significantly (P < 0.01) reduced the ulcer index and significantly (P < 0.01) increased the gastric pH of both Aspirin and aspirin-induced ulcer mice. The observations confirm that MERS whole plant has antiulcer activities.