ANTIBACTERIAL ACTIVITY OF Phyllanthus emblica & Cinnamomum verum FORMULATION MEDIATED SILVER NANOPARTICLES AGAINST ORAL PATHOGENS

Silver nanoparticles (AgNPS) are one of the broader nanoparticles with antibacterial properties and are considered toxic to disease causing agents. This is due to the effect of surface enhancement that results in increasing the reactivity of nano crystalline materials. When the particles are in nanometer range, their antimicrobial properties increase by more than 99% which have been shown to be related to shape, size & functional groups in nanoparticles. Green synthesis of silver nanoparticles using herbal products has received much attention due to its low cost and environmental compatibility, lack of pollutants and toxic substances.

Aim: To determine the antibacterial activity of Phyllanthus emblica and Cinnamomum verum fruit formulation based silver nanoparticles against oral pathogens.

Materials and Methods: Conical flask, distilled water, filter paper, fruit extract powder, petri- disks.

Results: Our results exhibited significant antibacterial action against oral pathogens. The diameter of the zone of inhibition observed during antibacterial activity assessment indicates maximum activity against staphylococcus aureus followed by Lactobacillus, Enterococcus faecalis & Streptococcus mutans. AgNPS may attach to the cell membrane surface and interrupt permeability and respiration association functions. Morenos et-al. Suggest that there is a possibility of AgNPS penetrating the cells of bacteria where they cause damage by interacting with the DNA.

Conclusion: Our findings suggest that Phyllanthus emblica and Cinnamomum verum based AgNPS has a significant antibacterial activity against oral pathogens. Hence it can be used as an effective therapeutic agent against various oral diseases by incorporating it in the toothpaste and mouthwash.