Cytogenetic Study in Male Infertility

Infertility is a serious clinical, social, and economic concern. Infertility affects not only one's ability to have children, but also one's emotional, psychological, social, and familial well-being. It affects approximately 15% of reproductive-age couples. For many years, it was assumed that the majority of reproductive issues could be attributed to the female partner, but recent research has shown that nearly 40-50 percent of infertility is caused by a male factor. Male factor infertility has been associated with a variety of abnormalities, including sperm number, motility, and morphology. Seminal analysis is the primary investigation for men despite being a poor predictor of sperm function and male fertility. ICSI (Intra cytoplasmic sperm injection) is the most recent development in the treatment of male infertility enabling couples who were previously deemed infertile to produce offsprings. As a result, the risk of genetic infertility increasing in future generations, as demonstrated by male infertility, exists. Thus, identifying genetic factors in infertile couples has become good practice for appropriate management of the infertile couple.