Medicinal Effects of the Mixture of Lime (Citrus aurantifolia) Juice and Ogogoro (Local Gin) on Ascariasis and its Assessment on Hepato-Renal Inflammatory Biomarkers in Ikotun Egbe Lagos State Nigeria

The present study investigate the medicinal effects of Mixture of Lime (Citrus aurantifolia) Juice and Ogogoro (Local gin) on Ascariasis and its Assessment on Hepato-Renal Inflammatory Biomarkers in Ikotun Egbe Lagos State Nigeria. Ascaris lumbricoides causes ascariasis, an infection of the small intestine. The goal of this study was to analyse the medicinal potency of a blend of lime (Citrus aurantifola) juice and ogogoro (Local gin) juice on ascariasis, as well as its effects on hepato-renal and inflammatory biomarkers. Helminthes infections occur mostly in the tropical regions worldwide and is one of the commonest causes of infant and childhood mortality in developing countries. Thirty primary school children whose stool samples upon microscopical examination at x40 were found to have 2+ ova of Ascaris lumbricoides (experimental group) and another thirty whose stool samples had no ova of Ascaris lumbricoides (control group) were recruited for this study. Each of the subjects in the experimental group was administered orally with ten milliliters of the mixture twice daily for five consecutive days. Two weeks after the completion of this oral administration, their stool samples were re-examined microscopically using x40 objective and it revealed that there was a significant reduction in the infection with ova of Ascaris lumbricoides from 2+ to nil in 70% of the primary school children in the experimental group. This may be suggestive of the medicinal potency of this mixture against Ascaris lumbricoidesas .Thereafter, five milliliters of blood specimens were collected into lithium heparin anti-coagulated bottles from each subject in the control and experimental groups respectively. The specimens were spun and the resulting plasma was utilised to assess hepato-renal and inflammatory biomarkers quantitatively, which revealed no statistically significant changes (p>0.05) when compared.. In conclusion, our investigation has revealed the medicinal potency of this mixture in the treatment of ascariasis, and its usage is advised.